About 5 results found for searched term "NEDD8-activating Enzyme" (0.147 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2189 | Pevonedistat (MLN4924) | NEDD8-activating Enzyme |
| MLN-4924; MLN 4924; Pevonedistat | ||
| Pevonedistat (MLN4924) is a first-of-its-kind (first-in-class) small molecule inhibitor of Nedd8 activating enzyme (NAE) with an IC50 of 4 nM. | ||
| M14477 | Pevonedistat hydrochloride | NEDD8-activating Enzyme |
| MLN4924 hydrochloride | ||
| Pevonedistat hydrochloride (MLN4924 hydrochloride) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM. | ||
| M14478 | TAS4464 hydrochloride | NEDD8-activating Enzyme |
| TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM. | ||
| M45362 | NAE-IN-M22 | NEDD8-activating Enzyme |
| NAE-IN-M22 is a potent, selective, and reversible inhibitor of NEDD8-activating enzyme (NAE) in the micromolar range. In addition, NAE-IN-M22 inhibits the growth of various cancer cells and induces apoptosis in A549 cells. | ||
| M45363 | ZM223 hydrochloride | NEDD8-activating Enzyme |
| ZM223 hydrochloride is a potent, orally active, non-covalent NEDD8 activating enzyme (NAE) inhibitor. | ||
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